diff --git a/CHANGELOG.md b/CHANGELOG.md
index 3584e33..9c5015b 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -13,6 +13,7 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 - Sending a non UTF8 body while having a `json` matcher registered will not raise a `UnicodeDecodeError` anymore.
 - `match_params` is now handling `bool`, `int` and `float` values in addition to `str`. Only str values were previously expected.
 - A meaningful error will now be returned when a callback that does not return an `httpx.Response` is called.
+- Responses with a `Content-Encoding` (such as `gzip`) provided via `content` can now be read by the client. They previously failed with `httpx.DecodingError`.
 
 ### Removed
 - python `3.10` is not supported anymore.
diff --git a/README.md b/README.md
index 33ff065..f1fd4e4 100644
--- a/README.md
+++ b/README.md
@@ -4,7 +4,7 @@
 <a href="https://pypi.org/project/pytest-httpx/"><img alt="pypi version" src="https://img.shields.io/pypi/v/pytest_httpx"></a>
 <a href="https://github.com/Colin-b/pytest_httpx/actions"><img alt="Build status" src="https://github.com/Colin-b/pytest_httpx/workflows/Release/badge.svg"></a>
 <a href="https://codecov.io/gh/Colin-b/pytest_httpx" ><img alt="Coverage" src="https://codecov.io/gh/Colin-b/pytest_httpx/branch/master/graph/badge.svg?token=U2PJFVMCAL"/></a>
-<a href="https://codecov.io/gh/Colin-b/pytest_httpx/tests"><img alt="Number of tests" src="https://img.shields.io/badge/tests-346 passed-blue"></a>
+<a href="https://codecov.io/gh/Colin-b/pytest_httpx/tests"><img alt="Number of tests" src="https://img.shields.io/badge/tests-354 passed-blue"></a>
 <a href="https://pypi.org/project/pytest-httpx/"><img alt="Number of downloads" src="https://img.shields.io/pypi/dm/pytest_httpx"></a>
 </p>
 
diff --git a/pytest_httpx/_httpx_mock.py b/pytest_httpx/_httpx_mock.py
index 5b7468d..e35ac4f 100644
--- a/pytest_httpx/_httpx_mock.py
+++ b/pytest_httpx/_httpx_mock.py
@@ -369,4 +369,6 @@ def _unread(response: httpx.Response) -> httpx.Response:
     response.is_closed = False
     if hasattr(response, "_content"):
         del response._content
+    if hasattr(response, "_decoder"):
+        del response._decoder
     return response
diff --git a/tests/test_httpx_async.py b/tests/test_httpx_async.py
index f045bd8..8dfa039 100644
--- a/tests/test_httpx_async.py
+++ b/tests/test_httpx_async.py
@@ -1,4 +1,5 @@
 import asyncio
+import gzip
 import math
 import os
 import re
@@ -921,6 +922,51 @@ async def test_with_headers(httpx_mock: HTTPXMock) -> None:
         )
 
 
+@pytest.mark.asyncio
+async def test_with_gzip_content_encoding(httpx_mock: HTTPXMock) -> None:
+    httpx_mock.add_response(
+        url="https://test_url",
+        content=gzip.compress(b"test content 1"),
+        headers={"Content-Encoding": "gzip"},
+    )
+
+    async with httpx.AsyncClient() as client:
+        response = await client.get("https://test_url")
+        assert response.content == b"test content 1"
+
+
+@pytest.mark.asyncio
+async def test_stream_with_gzip_content_encoding(httpx_mock: HTTPXMock) -> None:
+    httpx_mock.add_response(
+        url="https://test_url",
+        content=gzip.compress(b"test content 1"),
+        headers={"Content-Encoding": "gzip"},
+    )
+
+    async with (
+        httpx.AsyncClient() as client,
+        client.stream(method="GET", url="https://test_url") as response,
+    ):
+        chunks = [chunk async for chunk in response.aiter_bytes()]
+        assert b"".join(chunks) == b"test content 1"
+
+
+@pytest.mark.asyncio
+async def test_callback_with_gzip_content_encoding(httpx_mock: HTTPXMock) -> None:
+    def custom_response(request: httpx.Request) -> httpx.Response:
+        return httpx.Response(
+            status_code=200,
+            content=gzip.compress(b"test content 1"),
+            headers={"Content-Encoding": "gzip"},
+        )
+
+    httpx_mock.add_callback(custom_response, url="https://test_url")
+
+    async with httpx.AsyncClient() as client:
+        response = await client.get("https://test_url")
+        assert response.content == b"test content 1"
+
+
 @pytest.mark.asyncio
 async def test_requests_retrieval(httpx_mock: HTTPXMock) -> None:
     httpx_mock.add_response(
diff --git a/tests/test_httpx_sync.py b/tests/test_httpx_sync.py
index 9f837ca..da52f61 100644
--- a/tests/test_httpx_sync.py
+++ b/tests/test_httpx_sync.py
@@ -1,3 +1,4 @@
+import gzip
 import os
 import re
 from collections.abc import Iterable
@@ -834,6 +835,47 @@ def test_with_headers(httpx_mock: HTTPXMock) -> None:
         )
 
 
+def test_with_gzip_content_encoding(httpx_mock: HTTPXMock) -> None:
+    httpx_mock.add_response(
+        url="https://test_url",
+        content=gzip.compress(b"test content 1"),
+        headers={"Content-Encoding": "gzip"},
+    )
+
+    with httpx.Client() as client:
+        response = client.get("https://test_url")
+        assert response.content == b"test content 1"
+
+
+def test_stream_with_gzip_content_encoding(httpx_mock: HTTPXMock) -> None:
+    httpx_mock.add_response(
+        url="https://test_url",
+        content=gzip.compress(b"test content 1"),
+        headers={"Content-Encoding": "gzip"},
+    )
+
+    with (
+        httpx.Client() as client,
+        client.stream(method="GET", url="https://test_url") as response,
+    ):
+        assert b"".join(response.iter_bytes()) == b"test content 1"
+
+
+def test_callback_with_gzip_content_encoding(httpx_mock: HTTPXMock) -> None:
+    def custom_response(request: httpx.Request) -> httpx.Response:
+        return httpx.Response(
+            status_code=200,
+            content=gzip.compress(b"test content 1"),
+            headers={"Content-Encoding": "gzip"},
+        )
+
+    httpx_mock.add_callback(custom_response, url="https://test_url")
+
+    with httpx.Client() as client:
+        response = client.get("https://test_url")
+        assert response.content == b"test content 1"
+
+
 def test_requests_retrieval(httpx_mock: HTTPXMock) -> None:
     httpx_mock.add_response(
         url="https://test_url", method="GET", content=b"test content 1"