diff --git a/sdk/__tests__/NetworkInterceptor.test.ts b/sdk/__tests__/NetworkInterceptor.test.ts
index 1ee3f41..90a8165 100644
--- a/sdk/__tests__/NetworkInterceptor.test.ts
+++ b/sdk/__tests__/NetworkInterceptor.test.ts
@@ -32,6 +32,12 @@ class FakeXMLHttpRequest {
     }
   }
 
+  removeEventListener(type: string, listener: () => void) {
+    if (type === 'loadend') {
+      this.listeners = this.listeners.filter(existing => existing !== listener);
+    }
+  }
+
   complete() {
     this.readyState = this.DONE;
     this.listeners.forEach(listener => listener());
@@ -111,6 +117,21 @@ describe('NetworkInterceptor', () => {
     expect(xhr.listenedTo).not.toContain('progress');
   });
 
+  it("doesn't keep a response listener per request when an XMLHttpRequest is reused", () => {
+    const callbacks = createCallbacks();
+    installNetworkInterceptor(callbacks);
+
+    const xhr = new XMLHttpRequest() as unknown as FakeXMLHttpRequest;
+
+    for (let i = 0; i < 3; i++) {
+      xhr.open('GET', 'https://example.com/items');
+      xhr.send();
+      xhr.complete();
+    }
+
+    expect(callbacks.onResponse).toHaveBeenCalledTimes(3);
+  });
+
   it('still opens and sends the request when a callback throws', () => {
     installNetworkInterceptor({
       onOpen: () => {
diff --git a/sdk/__tests__/RealUserMonitor.test.ts b/sdk/__tests__/RealUserMonitor.test.ts
index 7e69c77..f29deee 100644
--- a/sdk/__tests__/RealUserMonitor.test.ts
+++ b/sdk/__tests__/RealUserMonitor.test.ts
@@ -30,6 +30,12 @@ class FakeXMLHttpRequest {
     }
   }
 
+  removeEventListener(type: string, listener: () => void) {
+    if (type === 'loadend') {
+      this.listeners = this.listeners.filter(existing => existing !== listener);
+    }
+  }
+
   complete() {
     this.readyState = this.DONE;
     this.listeners.forEach(listener => listener());
diff --git a/sdk/src/NetworkInterceptor.ts b/sdk/src/NetworkInterceptor.ts
index fd67892..7abcc8e 100644
--- a/sdk/src/NetworkInterceptor.ts
+++ b/sdk/src/NetworkInterceptor.ts
@@ -68,8 +68,15 @@ const patchXMLHttpRequest = () => {
     if (active && fetchCallDepth === 0) {
       runSafely('send', () => active.onSend(this));
       // loadend rather than readystatechange: in React Native, a readystatechange listener turns on incremental
-      // response updates from native, which completion alone doesn't need
-      this.addEventListener('loadend', () => runSafely('response', () => active.onResponse(this)));
+      // response updates from native, which completion alone doesn't need. The listener removes itself so that an
+      // XMLHttpRequest reused after abort() doesn't keep one per request; { once: true } can't be used, because React
+      // Native's XMLHttpRequest.addEventListener drops the options argument
+      const onLoadEnd = () => {
+        this.removeEventListener('loadend', onLoadEnd);
+        runSafely('response', () => active.onResponse(this));
+      };
+
+      this.addEventListener('loadend', onLoadEnd);
     }
 
     return (send as (...sendArgs: any[]) => void).apply(this, args);